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Although typical people use the word “antihistamine” to describe drugs for treating allergies, doctors and scientists use the term to describe a class of drug that opposes the activity of histamine receptors in the body.-receptor are used to treat allergic reactions in the nose (e.g., itching, runny nose, and sneezing) as well as for insomnia.

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The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.Claritin-D 24 hour (10mg loratadine 240mg psuedophedrine) Dosing (Adult): one tablet po qd. Approval: 2013 Mechanism of Action: Carbinoxamine is an H1 receptor antagonist (antihistamine) that exhibits anticholinergic (drying) and sedative properties.Claritin-D 24 Hour Extended Release Tablets should generally be avoided in patients with hepatic insufficiency. Antihistamines compete with histamine for receptor sites on effector cells.Dosing:: one tablet twice daily for adults and children 12 years of age and older (should be taken on an empty stomach).

A dose of one tablet once daily is recommended as the starting dose in patients with decreased renal function.

Diphenhydramine hydrochloride in the injectable form has a rapid onset of action. Management of pruritus: Oral: 25 mg 3-4 times/day Intravenous, intra-arterial, and subcutaneous administration are Adult (usual) Allergy: 25 mg orally at bedtime or 12.5 mg orally before meals and at bedtime. Please review the latest applicable package insert for additional information and possible updates.

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