Mitchell finished with 16 points, four rebounds, three assists and four steals, but his Cardinals fell to the Cavaliers by a 71-55 score.
Mitchell shot 6 of 17 from the field, while Louisville, as a team, shot 37 percent from the floor.
Mitchell, who is averaging a team-best 15.0 points per game, is currently slated to go in the first round, 24th overall, in Draft Express.com's latest mock draft.
Virginia Cavaliers guard Ty Jerome (11) dribbles the ball ahead of Louisville Cardinals guard Donovan Mitchell (45) and Cavaliers guard Devon Hall (0) in the second half at John Paul Jones Arena. Another local player, New Rochelle native and Iona Prep graduate Ty Jerome, came off the bench for Virginia.
March 29, 2015 Jamie Rhodes/USA TODAY Sports Louisville coach Rick Pitino has urged current and former players and staff to talk freely and openly with U of L?
s private investigator, former NCAA enforcement staffer Chuck Smrt.
On Monday, Donovan Mitchell was given an increased leadership role by Louisville head coach Rick Pitino.
The Elmsford native was named a team captain for the Cardinals, who had just jumped up to fourth in the national rankings. 12 Virginia, however, proved to be too much for Mitchell and his short-handed teammates.
The fourth-ranked Cardinals Saturday will try to end a four-game skid against the Wildcats. Phillip, File) Sam Upshaw Jr./The C-J Rick Pitino congratulates Mangok Mathiang during a game against Virginia Tech last season.During his talk he used Demetrius Dunlap, age 10, as a basket to demonstrate how putting the proper arc on the ball. CHESTNUT HILL, MA - JANUARY 28: Head coach Rick Pitino of the Louisville Cardinals yells to his team in the first half against the Boston College Eagles during the game at Conte Forum on January 28, 2015 in Chestnut Hill, Massachusetts.